Not just the joints: A review article on the comorbidities of JHS/HEDS

Ehlers–Danlos Syndrome - Hypermobility Type: A Much Neglected Multisystemic Disorder

Yael Gazit, Giris Jacob, and Rodney Grahame.

Excerpt from abstract:
Throughout the years, extra-articular manifestations have been described, including cardiovascular, autonomic nervous system, gastrointestinal, hematologic, ocular, gynecologic, neurologic, and psychiatric manifestations, emphasizing the multisystemic nature of EDS-HT. Unfortunately , EDS-HT is underrecognized and inadequately managed, leading to neglect of these patients, which may lead to severe disability that almost certainly could have been avoided. In this review article we will describe the known manifestations of the extra-articular systems.