IF YOU CAN'T CONNECT THE ISSUES, THINK CONNECTIVE TISSUES!

If you can't connect the issues, think connective tissues! 

Connecting the dots between Ehlers-Danlos Syndrome and related conditions. 






This presentation  by Dr. Heidi Collins is a must read for anyone wanting to know more about Ehlers-Danlos Syndrome. 

In particular, it has information on:
  1. What is connective tissue.
  2. How EDS differs from auto-immune connective tissue diseases (like SLE).
  3. The heterogeneous and multisystemic presentation of EDS.
  4. How EDS-HT is more than just hypermobility.
  5. The controversies and lack of awareness in medical community about EDS. 

Key Takeaways:

NO TWO ZEBRAS HAVE THE SAME STRIPES  
Heterogeneity of EDS — and heterogeneity of people in general — ultimately leads to:
• a broad spectrum of clinical presentations
• widely variable disease progressions
• treatments varying in efficacy from person to person
"Penetrance is believed to be 100%, although expressivity is extremely variable, and careful examination may be required to demonstrate typical features, especially in adult men who have never experienced a major joint complication or significant pain." (Levy HP. Ehlers-Danlos syndrome, hypermobility type. In: Pagon RA, Bird TD, Dolan CR, Stephens K, Adam MP, editors. GeneReviews. Seattle, Wash, USA: University of Washington; 2010.)